Structure-guided discovery approach identifies potential lead compounds targeting Mpro of SARS-CoV-2
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چکیده
منابع مشابه
Glycan arrays lead to the discovery of autoimmunogenic activity of SARS-CoV.
Using carbohydrate microarrays, we characterized the carbohydrate binding activity of SARS-CoV neutralizing antibodies elicited by an inactivated SARS-CoV vaccine. In these antibodies, we detected undesired autoantibody reactivity specific for the carbohydrate moieties of an abundant human serum glycoprotein asialo-orosomucoid (ASOR). This observation provides important clues for the selection ...
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ژورنال
عنوان ژورنال: VirusDisease
سال: 2020
ISSN: 2347-3584,2347-3517
DOI: 10.1007/s13337-020-00627-6